About Us
The UConn-Storrs Mass Spectrometry Facility was inaugurated on August 1, 2007. The Facility recognizes the increasingly important role of Mass Spectroscopy in determining small molecule and protein structure, purity, identity and in analytical aspects of drug design. The Mass Spectrometry Facility serves the analytical needs for a diverse group of investigators from Molecular and Cell Biology, Chemistry, The Institute of Material Sciences, Nutrition, Chemical Engineering, Animal Sciences, Plant Sciences, Anthropology, Geology, Marine Sciences (Avery Point), Pharmacy and the UConn Health Center (medical & dental). Off-campus users include CCSU, ECSU, Connecticut College, Harvard University, Connecticut Agricultural Experiment Station, Connecticut Forensic Lab and several corporations in the private sector.
The Mass Spectrometry Facility directly supports and impacts research programs in the following areas:
- Structure-function relationships
- Structure of proteins
- Nanomaterial analysis
- Small molecule identification and quantification
- Conformational analysis
- Pharmaceutical chemistry
- Analytical chemistry
- Chemical synthesis
- Mass Spec methods development
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Services and Instrumentation:
Q-TOF equipped with an API ionization source operating in either electrospray (ESI) or atmospheric pressure chemical ionization (APcI) mode useful for a broad range of molecules to ~ 12 kDa. The instrument is capable of precision mass determination as well as structural elucidation by tandem mass spectrometry (MS/MS). A dedicated HPLC affords compound separation in mixtures.
MALDI-TOF equipped with a laser ionization source capable of mass determinations to ~ 300 kDa.
Facility Use Fees:
Please click here to view the current fee schedule (PDF format).
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